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Diaper rash is an age-old problem blamed on everything from teething to diet. Pediatricians now believe it's usually caused by moisture, chafing, yeast or bacterial infections, prolonged contact with soiled diapers or allergies to diaper materials. To treat and prevent diaper rash, change diapers often, gently clean the area and let it air-dry, apply a thick layer of protective ointment and keep the diaper loose to prevent rubbing. Skip baby wipes to avoid further irritation and call your pediatrician if the rash gets worse.